Type I Glanzmann's Thrombasthenia in a Great Pyrenees Dog
نویسندگان
چکیده
منابع مشابه
Chondrodysplasia in five Great Pyrenees.
Five disproportionate, short-limbed, short-trunked (dwarf) Great Pyrenees pups were examined. The mode of inheritance was compatible with a simple autosomal recessive trait, and skeletal radiography revealed flaring of the metaphyses of all long bones and the costochondral junctions of the ribs. Vertebral bodies were poorly ossified and short, and had a beak-like extension on the caudal metaphy...
متن کاملMicroparticle Formation and Platelet Shrinkage in Type-I Glanzmman Thrombasthenia Platelets
Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage ...
متن کاملA simple, novel and robust test to diagnose type I Glanzmann thrombasthenia.
Glanzmann thrombasthenia (GT) is an inherited bleeding disorder due to either absence or dysfunction of fibrinogen binding receptors, i.e either GPIIb (GPIIβ) or GPIIIa (GPIIIα) on platelet membrane. The complete fibrinogen receptor, i.e. GPIIβGPIII which binds fibrinogen on activated platelets involves association of these two glycoproteins. Absence of either or both of these receptors can, th...
متن کاملType I Glanzmann Thrombasthenia Patients From the Iraqi - Jewish and Arab Populations in Israel Can Be
A sensitive immunoblot technique for platelet glycoprotein lIla (GPllla) was used to analyze the platelets of patients living in Israel who meet the diagnostic criteria for type I Glanzmann thrombasthenia. When reacted with solubilized normal platelets, a rabbit antiserum to GPIIIa identified a major band at molecular weight (mol wt) 90.000 and three additional minor bands at Mr 1 1 0.000. 81 ....
متن کاملAsymmetric Lumbosacral Transitional Vertebra (LTV) Type-3 in a German Shepherd Dog: A Case Report
Case Description- In the present study, a seven-year-old German shepherd female dog was referred to Veterinary Hospital of Shahid Chamran University of Ahvaz, with a two-week history of intermittent lameness and lumbosacral pain. Clinical Findings- On general examination, the vital parameters were within normal limits. A ventrodorsal (VD) radiograph of the pelvis and lumbosacral spine was take...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 1996
ISSN: 0300-9858,1544-2217
DOI: 10.1177/030098589603300504